immunoperoxidase) is a useful procedure because it is performed on formalin-fixed material and can discriminate between PPR and rinderpest when performed with specific monoclonal antibodies. Histology revealed necrohemorrhagic enteritis and abomasitis with myriad nuclear and cytoplasmic viral inclusion bodies. Histopathological features were also compared according to the severity, through subgroup analysis within each subtype group. PPR is listed in the World's largest and most authoritative dictionary database of abbreviations and acronyms The Free Dictionary Histopathology combined with immunohistochemical staining (e.g. Proceedings of the International workshop held at IITA Ibadan, Nigeria, 24-26 September. Author Guidelines. © 2020 Springer Nature Switzerland AG. In the regions where PPR occurs in an epizootic form it may have dramatic consequences for animal owners due to high mortality rates. 4.6 Histopathology. Peste des petits ruminants (PPR) is a devastating disease that generally affects sheep and goats, mostly in Asia, the Middle East and Africa. Since no studies with live animals were conducted in this work, an ethical approval was not required. HistoPATHOLOGY 1. PPR is an acute highly contagious viral disease of goats, less commonly sheep and closely related wild bovidae, and is clinically mimics cattle plague, ... For histopathology slices of lymph node, spleen, tonsils, and mucosal lesions are collected in 10 % formalin saline for. It is closely related to Rinderpest, measles, canine distemper and morbilliviruses of marine mammals and is the most economically important viral disease of small ruminants [1-3]. Peste des petits ruminants (PPR) is an acute or subacute viral disease of goats and sheep characterized by fever, necrotic stomatitis, gastroenteritis, pneumonia, and sometimes death. J Gen Virol 91:2885–2897. the histopathology of samples from infected animals was consistent with those found in naturally infected animals. Animal Front 4:14–20, Kinne J, Kreutzer R, Kreutzer M, Wernery U, Wohlsein P (2017) Peste des petits ruminants in Arabian wildlife. Pustular lesions usually have a … Aims and Scope; Submitting your Manuscript 2.1 Submission Checklist 2.2 Article Preparation Support 2.3 Review Process 2.4 Manuscript Structure 2.5 Graphical Abstract 2.6 Submission of a Revised Version; Post-acceptance; 1. Recognition of PPR as a problem has increased in the 1990s, partly as a result of surveillance activities of the global rinderpest eradication programme (GREP), but also because of the capacity of the infection to invade disease-free countries. Histopathology is an international journal intended to be of practical value to surgical and diagnostic histopathologists, and to investigators of human disease who employ histopathological methods. The tissue that is studied comes from a biopsy or surgical procedure whereby a sample of the suspect tissue is selected and sent to the laboratory. The Endocrine Pancreas 3. Berkowitz, A., Avni-Magen, N., Bouznach, A. et al. PPR infection is most commonly recorded among the sheep population in India. Histopathological assessment of PPRV-infected tissues demonstrates many of the. Peste des petits ruminants virus. In areas where peste des petits ruminants (PPR) is endemic, most rinderpest-like syndromes are more likely to be PPR. Confirmatory tests include histopathology, polymerase chain reaction (PCR), virus isolation (VI), and virus neutralization (VN). Confirmatory tests include histopathology, polymerase chain reaction (PCR), virus isolation (VI), and virus neutralization (VN). Majority were grade 2 tumors out of which 81% showed pPR and 18.5% showed pCR. INTRODUCTION Peste des petits ruminants (PPR), is an acute, highly contagious and economically important transboundary viral disease of sheep and goats associated with high morbidity and mortality (Balamurugan et al., 2014). The histopathology and immunohistochemistry of most of the target tissues (intestines, tongue, lungs and lymph nodes) showed positive signal for PPR … Peste des petits ruminants (PPR) is a devastating disease that generally affects sheep and goats, mostly in Asia, the Middle East and Africa. Copyright © 2020 Elsevier B.V. or its licensors or contributors. Key words: goats, histopathology, immunomodulation, Nigella Sativa, PPR., OIE: The OIE official info Google Scholar, Wang Z, Bao J, Wu X, Liu Y, Li L, Liu C, Suo L, Xie Z, Zhao W, Zhang W, Yang N, Li J, Wang S, Wang J (2009) Peste des petits ruminants virus in Tibet, China. . Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Our primary purpose is to publish advances in pathology, in particular those applicable to clinical practice and contributing to the better understanding of human disease. In both species, significant levels of virus were detected in the lymph nodes, lymphoid tissues and digestive tract at 6 dpi. The disease has been declared a target for global eradication. The histopathology, IHC, and quantitative RT-PCR results from both sheep and goats also provide some insight into the disease progression of PPR in small ruminants. Vet Microbiol 197:137–141. Below is the link to the electronic supplementary material. Following the first description of PPR it was postulated that the causal agent was a variant strain of rinderpest adapted to small ruminants (Mornet et al., 1956).This was confirmed by the present knowledge on the epidemiology of the two diseases which occur separately … Oran Erster. . Vet Microbiol 22:341–352, Perl S, Alexander A, Yakobson B et al (1994) Peste des petits ruminants (PPR) of sheep in Israel. Asaf Berkowitz and Oran Erster contributed equally to this work. In tumors that showed a pPR, 27.1% were grade 1 tumors, 27.1% were grade 2 tumors, and 2.1% were grade 3 tumors (Table 5). Histopathology combined with immunohistochemical staining (e.g. Despite its high prevalence in domestic flocks and its high seroprevalence among wildlife, it is rarely reported as a fulminant disease in wild ruminant species (with the exception of Central Asia). The frequency of each histopathological finding was compared between subtypes.

histopathology of ppr

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